The Study of Interaction Activity of Nickel (ll) Phthalocyanine Complex Bearing Tetra Substituted Phenoxy-3-Methoxybenzoic Acid Groups with DNA

Nickel phthalocyanine complex containing 4-(3,4-dicyanophenoxy)-3-methoxybenzoic acid group was synthesized and specified by way of FT-IR, NMR, UV/Vis procedures. The binding PcNi to CT-DNA examined via electronic absorption titration, emission melting temperature, viscosity measurement, agarose gel electrophoresis technics, respectively. DNA interaction activity against studied UV/Vi titrations, fluorescence spectra, farther conducting point, procedures in the buffer a pH 7.02. obtained outcomes from these methods demonstrated that indicated substantial affinity intercalating constant 1.31 x 106 m-1. Further, on investigated which technique this procedure exhibits strong DNA.